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- _5 value "Interestingly, other LRR domain-containing proteins have also been demonstrated to interact with receptor tyrosine kinases. Decorin, a secreted proteoglycan containing nine LRRs, has been shown to interact with the EGF receptor and ErbB2 to initially enhance their activities (27, 28). Decorin interaction with receptors has been suggested to mediate prolonged receptor down-regulation and the inhibition of cellular growth through enhanced expression of p21waf1 (29)." provenance.
- _5 wasQuotedFrom 15345710 provenance.