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- _3 value "Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice.We report here that overexpression of cyclin D1 resulted in abnormal mammary cell proliferation including the development of mammary adenocarcinomas. We conclude that overexpression of cyclin D1 deregulates cell proliferation and can induce tumorigenic changes in mammary tissues, suggesting that cyclin D1 indeed plays an important oncogenic role in breast cancer." provenance.
- _3 wasQuotedFrom 8208295 provenance.