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- _3 value "To indirectly examine the role of CS-1 FN in mediating monocyte adhesion to MAEC, we used a peptide that specifically blocks CS-1-mediated monocyte adhesion (43). This peptide blocks the LDV-binding site for CS-1 FN on VLA-4 (43). As shown in Fig. 14, monocyte adhesion to LOTG EC was decreased by 50% in the presence of the CS-1 FN blocking peptide. Use of a blocking antibody to VCAM-1 (44) also reduced adhesion by 30% (Fig. 14). Use of blocking antibodies to both 4 and 2 integrins (44) in monocytes completely prevented adhesion." provenance.
- _3 wasQuotedFrom 14676201 provenance.