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- _5 value "As shown in Figs. 3A-C, TNF-alpha induced transient phosphorylation of ERK1/2, JNK, and p38 in HUVECs, with the maximal response being seen within 15 min, followed by a decline to the basal level within 60 min. In addition, pretreatment for 1 h with the indicated concentrations of PD98059 (an ERK1/2 inhibitor), SP600125 (a JNK inhibitor), or SB203580 (a p38 inhibitor) inhibited the TNF-alpha-induced VCAM-1 expression seen at 6 h of TNF-alpha treatment (Figs. 3D-F)." provenance.
- _5 wasQuotedFrom 21767632 provenance.