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- _5 value "ErbB2 appears to have a special role, as its functional inactivation blocked EGF-, BTC-, and HRG-induced breast cancer cell migration [126]. Since ErbB2-containing heterodimers promote strong activation of the MAPK and PI-3K pathways [12,13], known to have important roles in migration [125-127], cells lacking ErbB2 might fail to migrate simply because these pathways are weakly stimulated." provenance.
- _5 wasQuotedFrom 12648469 provenance.