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- _3 value "Skeletal Muscle. Insulin receptor function has been inhibited in two ways: muscle-specific knockout of the insulin receptor (MIRKO; Bruning et al., 1998) and muscle-specific expression of a dominant-negative mutant insulin receptor (IR-A1134T) in transgenic mice (Moller et al., 1996). In both models, skeletal muscle was insulin resistant when studied in vitro." provenance.
- _3 wasQuotedFrom 10199397 provenance.