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- _2 value "The capillary bed is known to be hyperpermeable in patients with sepsis, thereby leaking albumin. However, the extent to which altered liver biosynthesis and rates of catabolism contribute to the plasma albumin deficiency seen in sepsis and critical illness remains uncertain. Indeed, the half-life of HSA in patients with hypoalbuminemia supported with total parenteral nutrition is only 9 days, although rates of catabolism are normal.40 Moreover, catabolism actually may be decreased while the extracellular pool is increased, suggesting that HSA may be spared or protected." provenance.
- _2 wasQuotedFrom 15915465 provenance.