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- _5 value "Moreover, suppression of the JNK pathway in liver decreases wholebody insulin resistance and improves glucose tolerance in diabetic animal models (90). Furthermore, loss-of-function mutations in JNK-interacting protein 1, a negative and essential modulator of JNK (91), causes type 2 diabetes in humans (92)." provenance.
- _5 wasQuotedFrom 15793228 provenance.