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- _5 value "Those individuals vearing the intracellular R551 variant of the Il4a and no other intracellular variant, and those bearing no intracellular variant were selected. Introduction- doesn't distinguish between variants! After binding of Il4 and Il13, activation of the receptor-associated kinases (Jak) takes place, followed by the direct activation of IRS1/2 and STAT6 (an Il4 specific transcription factor) and further signal transduction cascades (e.g. IRS1/2 iniates PI3 kinase)" provenance.
- _5 wasQuotedFrom 12204103 provenance.