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- _6 value "To determine if ASK1 activates JNK in response to NO, Ask1?/? MEFs were treated with DETA-NO and phospho-JNK expression was determined by Western analysis. JNK is not phosphorylated in Ask1?/? MEFs after treatment with DETA-NO, but is phosphorylated in Bax?/?/Bak?/? MEFs (Figure 8AFigure 8). Furthermore, Ask1?/? MEFs treated with DETA-NO are protected from NO-induced cell death as measured by LDH release (Figure 8BFigure 8). " provenance.
- _6 wasQuotedFrom 19768117 provenance.