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- _5 value "293GHR cells were transiently transfected with an estrogen receptor-alpha expression plasmid and luciferase reporters with binding elements for STAT3 and STAT5 or the beta-casein promoter. Cotreatment with 17beta-estradiol (E(2)) resulted in a dose-dependent reduction in the response of all three reporters to GH to a maximum of 49-66% of control at 100 nM (P reduction was seen when E(2) was added 1-2 h after GH treatment." provenance.
- _5 wasQuotedFrom 12552091 provenance.