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- _4 value "L929sACrmA cells were treated for 16 hours with 1 microMolar geldanamycin followed by treatment with human TNF. Inhibition of caspase-8 blocks TNFR-1 induced apoptosis in the presence of geldanamycin. This suggests that the apoptotic process induced by TNF in the presence of geldanamycin is mediated through activation of caspase-8." provenance.
- _4 wasQuotedFrom 12441346 provenance.