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- _4 value "many, but not all, non-steroidal nuclear receptors are thought to be pre-bound to the HRE in a complex with corepressor proteins entry of the ligand into the LBD initiates changes int he conformation of the receptor that results in loss of corepressor proteins, recruitment of coactivator proteins and increased transcription identified oxysterols, such as 24S,25-epoxycholesterol, 20S-,22R-,24S- and 27-hydroxycholesterol, as activators of of Lxr" provenance.
- _4 wasQuotedFrom 11792716 provenance.