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- _2 value "SAC are cationic nonselective or K+ selective. Compared with VACCl, SAC activate fast upon mechanical stimulation. Kohl et al. (251) have suggested that fast activation of SAC can be involved in the beat-by-beat regulation of heart rate. SAC are inhibited by Gd3+ (383), streptomycin (151), and the spider toxin GsMTx-4 (42). Cooper and Kohl (99) reported that the chronotropic response of isolated pacemaker cells is inhibited by GsMTx-4, thus indicating functional expression of SAC in SAN cells." provenance.
- _2 wasQuotedFrom 18626064 provenance.