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- _3 value "CAPE and curcumin normalize enterocyte proliferation in Min/+ mice Previous studies show that normal migration of enterocytes from the crypts to the villus tips is inhibited in the Min/+ mouse and, consequently, the mucosal enterocytes of these animals have a reduced turnover rate (38). Consistent with this observation, we observed a decrease in proliferation of this cell population in previous studies of the Min/+ mouse (37,38). Effective chemopreventive drugs, such as sulindac (33) and aspirin (34), normalize intestinal cell proliferation and restore the enterocyte migration rate to the level of wild-type animals." provenance.
- _3 wasQuotedFrom 10783313 provenance.