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- _3 value "Data coming from mice lacking p110a regulatory subunits have shed light on the dual role of p85 in PI3K regulation in response to insulin (Katso et al., 2001). Heterozygous deletion of either p85a or b in mice leads, surprisingly, to increased sensitivity to insulin, whereas compound heterozygous mutants fail to activate PI3K in response to insulin." provenance.
- _3 wasQuotedFrom 18794886 provenance.