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- _3 value "In the WT recipient, plaques become rapidly exposed to a plasma environment containing a relative increase in HDL and decrease in non-HDL cholesterol, changes which are expected to promote cholesterol efflux from foam cells and thereby reverse inflammatory changes associated with the lipid loading of macrophages (e.g., refs. 18?20)....the expression of LXR, ABCA1, or SR-BI was increased in cells from the plaques placed in the WT recipient. In these same cells, there was decreased expression of the NF-B-target inflammatory genes MCP-1 and VCAM-1 (Fig. 4B)." provenance.
- _3 wasQuotedFrom 16537455 provenance.