Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RASQYulBXi8KeqnGKRM4ObAf2KmxizgD1MpNVhCpAcUNI#_5> ?p ?o ?g. }
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- _5 value "Binding of HGF/SF to its tyrosine kinase receptor c-Met stimulates multiple signal transduction pathways, leading to the activation of numerous transcription factors. HGF/SF-mediated phosphorylation of ATF-2 was reduced in the presence of either the p38 kinase-specific inhibitor SB203580, a dominant negative p38 mutant, the SAPK/JNK inhibitor JNK-interacting protein-1 (JIP-1), or the phosphatidylinositol 3-kinase (PI3K)-specific inhibitor LY294002. Activation of p38 kinase by HGF/SF was partially blocked by the PI3K-specific inhibitor as well" provenance.
- _5 wasQuotedFrom 11850817 provenance.