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- _4 value "the molecule has an essential role in controlling acute phase gene expression and provides hepatocellular protection after LPS challenge. Additionally, challenging hepatocyte-specific gp130 knockout animals with lipopolysaccharides (LPS) lead to an onset of acute liver injury with an increase of hepatocyte apoptosis associated with elevated tumor necrosis factor alpha (TNF-alpha) serum levels and reduced nuclear factor kappaB (NF-kappaB) activation in hepatocytes." provenance.
- _4 wasQuotedFrom 12891556 provenance.