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{ <http://www.tkuhn.ch/bel2nanopub/RASrqgWTcmrXTADfzE3xaiRzp1DNqSkkCUhGomO4zeJxM#_7> ?p ?o ?g. }
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Phosphorylation of Shc produces its binding to the adaptor protein Grb2, causing activation of the protooncogene ras, which is also upstream of the MAP kinase pathway.
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