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- _5 value "This mutant NF-YA, which sequesters NF-YB and NF-YC into a functionally inactive heterotrimer ( 32 ), significantly reduced activation of the MDR1 promoter by UV irradiation (Fig. 3 A ), indicating a role for NF-Y in the UV response......We have previously shown that the CCAAT box-binding protein, NF-Y, mediates MDR1 activation by the histone deacetylase inhibitors, trichostatin A and sodium butyrate, through the recruitment of the co-activator, P/CAF. (9632821)--[shows direct NF-Y subunit binding --DD]" provenance.
- _5 wasQuotedFrom 10644769 provenance.