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- _4 value "In the SAN, ICa,L is regulated by PKA (390) and by activated Ca2+/calmodulin-dependent protein kinase II (CaMKII) (509), which regulates the current activation and reactivation kinetics (509). Similarly, in ventricular cells, CaMKII facilitates opening of L-type channels in response to Ca2+ permeation, with consequent stimulation of ICa,L amplitude and slowing of current inactivation (135, 528)." provenance.
- _4 wasQuotedFrom 18626064 provenance.