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{ <http://www.tkuhn.ch/bel2nanopub/RATUMTocVrkWqHArxJ-3-LBSLiraGrpT-s_Hx8DPwRrbs#_5> ?p ?o ?g. }
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during insulin stimulation, IRS1 undergoes tyrosine phosphorylation and binds PI3K the binding of insulin to its receptor induces the phosphorylation of the cytosolic substrate IRS1 and IRS2
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