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{ <http://www.tkuhn.ch/bel2nanopub/RATZz6lJyT70uWfEDW1J9NHo5-C5CGN132YtOZbRqAwJI#_4> ?p ?o ?g. }
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The interaction of MDM2 with p53 inhibits p53 transcriptional activity and targets p53 for ubiquitin-dependent degradation. The ability of MDM2 to inhibit p53 functions is antagonized by the ARF oncosuppressor protein.
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