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- _3 value "Depletion of Nrf2 by siRNA resulted in a decline in Srx1 mRNA expression...and, conversely inhibition of expression of KEAP1 upregulated the transcript for Srx1 in BEAS2B cells (Fig. 3A).....The cells were exposed to various oxidative stressors such as H2O2 (200 ?M), TBHQ (50 ?M), and CS extract (100 ?g/ml) for 6 to 24 h. The NQO1 and Srx1 induction in response to these treatments was quantified by real-time RT-PCR. Srx1 expression was upregulated in response to treatment with all three oxidative stress-inducing agents (Figs. 3B?D)." provenance.
- _3 wasQuotedFrom 19027064 provenance.