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- _4 value "In the present study, we examined the effects of rosiglitazone (RGZ) (rosaglitazone is a Pparg agonist) on insulin release and synthesis in pancreatic beta-cell (INS-1). Insulin release and synthesis were stimulated by treatment with RGZ for 24h. RGZ upregulated the expressions of GLUT-2 and glucokinase (GCK). Moreover, it was found that RGZ increased the expression of BETA2/NeuroD gene which could regulate insulin gene expression." provenance.
- _4 wasQuotedFrom 18191635 provenance.