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- _5 value "o clarify the intracellular downstream signaling cascades of alpha -synuclein, we measured the activity of endogenous mitogen-activated protein kinases, such as extracellular signal-regulated protein kinase (ERK), c-Jun N-terminal kinase (JNK), and p38 kinase. When 10 �M alpha -synuclein was added, a significant increase of JNK (Fig. 1B) and a lower but marked activation of ERK and p38 activity (data not shown) were observed using anti-phospho-ERK, anti-phospho-JNK, and anti-active p38 antibodies. " provenance.
- _5 wasQuotedFrom 11316809 provenance.