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- _4 value "Osteoclast formation was higher in ovariectomized (OVX) mice than sham operated mice, ovariectomy also increased the mononuclear cell secretion of interleukin IL-1, tumor necrosis factor and M-CSF production. The production of M-CSF protein and mRNA via Tnf was lowered by the treatment of estrogen or TNFbp (TNFbp bound with equal affinity to TNF alpha and TNF beta and blocked Tnf activity) in ovariectomized bone marrow cells." provenance.
- _4 wasQuotedFrom 8910536 provenance.