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- _4 value "overproducing the PtdIns(3')phosphate phosphatase PTEN also attenuates insulin stimulation of Glut4 translocation. Although these two phosphatases [SHIP2 and PTEN] lead to the accumulation of different lipid products, activation or overproduction of both enzymes seems to attenuate insulin signaling by reducing PtdIns(3,4,5)P3 levels." provenance.
- _4 wasQuotedFrom 11849969 provenance.