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- _5 value "Genes were considered to be differentially expressed if they had a difference in expression level between the two conditions that was at least twofold and the extent of difference in expression was statistically significant (p ! 0.05) in a parametric Welsh-analysis of variance t-test. Only genes that showed concordant results in all three replicates were selected for further evaluation. Genes that differed significantly between wild-type Meis1 and the nonleukemogenic Meis1DHD mutant (lacking its DNAbinding domain) were then identified. With this approach 134 genes (70 increased and 64 decreased, Table 1) could be identified as significantly differentially expressed and linked to the oncogenicity of Meis1." provenance.
- _5 wasQuotedFrom 18375036 provenance.