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- _5 value "Figure 4B shows that Src is activated by cigarette smoke in the absence of the Src kinase inhibitors PP1 and PP2 and is inhibited in the presence of these compounds. Concurrently, EGFR Tyr-845 is phosphorylated in the absence of PP1 or PP2, whereas the phosphorylation is inhibited in the presence of these inhibitors, suggesting that Src kinase activation is responsible for the hyperphosphorylation of this site during cigarette smoke exposure (Fig. 4B)." provenance.
- _5 wasQuotedFrom 17971399 provenance.