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- _5 value "PA activity is controlled at three levels: (i) the expression of uPA and uPAR is upregulated by angiogenic growth factors (88, 147) and cytokines (245). (ii) Pro-uPA needs to be activated proteolytically and (iii) the activity of plasmin and uPA is regulated by a 2-antiplasmin and plasminogen activator inhibitors (PAIs), respectively (11, 19)." provenance.
- _5 wasQuotedFrom 11172729 provenance.