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- _3 value "How does 'resistance' occur? In addition to the hypoxia that often naturally accompanies tumour growth, anti-angiogenesis treatments can also contribute to hypoxia - an expected result of the loss of the oxygen-transporting blood vessels66.Unfortunately, hypoxia and high levels of VEGFA production provide some protection from cytotoxic drugs by inducing expression of anti-apoptotic genes" provenance.
- _3 wasQuotedFrom 12778130 provenance.