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- _7 value "Mcl-1 binds to the BH3-only proteins Bim, Bid, Bik, Noxa and Puma (Chen et al., 2005), as well as Bak (Cuconati et al., 2003). Binding to Bid and Bim protects against tumor necrosis factor-related apoptosisinducing ligand (TRAIL)-induced cell death. Either depletion of Mcl-1 (Nijhawan et al., 2003) or disruption of the interaction between Mcl-1 and Bak coincides with apoptosis following a cytotoxic stimulus" provenance.
- _7 wasQuotedFrom 17404574 provenance.