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- _4 value "Robertson et al. crossed ApoE-deficient mice with the TGF-?RII dominant-negative transgenic mice and found a six-fold increase in atherosclerotic lesion surface area, a three-fold increase in aortic root lesion size, and a one-hundred and twentyfive- fold increase in aortic IFN-? mRNA expression levels.33 In addition, the lesions contained increased inflammatory infiltration (macrophages and T cells) and decreased collagen content consistent with an unstable plaque phenotype.33" provenance.
- _4 wasQuotedFrom 16462725 provenance.