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- _5 value "We therefore tested whether GATA5 and NF-ATc collaborate in regulating endocardial transcription thereby affecting cell differentiation. For this, we used the GATA-dependent ET-1 promoter, which is preferentially regulated by GATA5 (Nemer et al., 1999Go). As shown in Fig. 6B, the ET-1 promoter is synergistically activated in TC13 cells by co-expression of GATA5 and NF-ATc suggesting that these two transcription factors act cooperatively to induce endocardial gene expression." provenance.
- _5 wasQuotedFrom 12163407 provenance.