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- _4 value "Experiments in vitro have shown that naive CD4 T cells initially stimulated in the presence of IL-12 and IFN-? tend to develop into TH1 cells.....The activation of TH1 cells by infected macrophages results in the synthesis of cytokines that both activate the macrophage and coordinate the immune response to intracellular pathogens. IFN-gamma and CD40 ligand synergize in activating the macrophage, which allows it to kill engulfed pathogens. " provenance.
- _4 wasQuotedFrom _3 provenance.