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- _3 value "Surface integrins have been shown to be critical regulators of endothelial cell migration in response to VEGF and NO. Here we found that VEGF-stimulated HUVECs exposed to CSE had a significant reduction in the expression of several surface integrins including ?v?3, ?v?5, ?5?1 and ?2?1 (Fig. 2C). Moreover, the adhesion of VEGF-stimulated HUVECs was significantly reduced following exposure to 10% CSE, suggesting an impairment of integrin activity/function (Fig. 2D)." provenance.
- _3 wasQuotedFrom 16806264 provenance.