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{ <http://www.tkuhn.ch/bel2nanopub/RAXZcL4l9mYVilGRwQ3ud68t_L5qyyyse2d0w11xoD3VA#_4> ?p ?o ?g. }
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In conclusion, Hdm2 functionally activates HIF-1 by inhibiting the FIH interaction with CAD, and the Hdm2 inhibition by nutlin-3 results in HIF-1 inactivation and vascular endothelial growth factor suppression.
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