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- _6 value "COS-7 cells were transiently transfected with expression vectors for SUMO-1 together with HDAC4 or HDAC4-K559R followed by immunoprecipitation using the anti-HDAC4 antibodies and an assay for histone deacetylase activity (Figure 4B). Although the two proteins were expressed at a similar level (inset), the HDAC activity associated with HDAC4-K559R was significantly reduced, to a level barely above that of endogenous HDAC4 (compare lane 3 with lanes 1 and 2)." provenance.
- _6 wasQuotedFrom 12032081 provenance.