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- _4 value "CRIM1 modulates BMP activity by affecting its processing and delivery to the cell surface. CRIM1 binding of BMP4 and -7 occurs when these proteins are co-expressed within the Golgi compartment of the cell and leads to (i) a reduction in the production and processing of preprotein to mature BMP, (ii) tethering of pre-BMP to the cell surface, and (iii) an effective reduction in the secretion of mature BMP." provenance.
- _4 wasQuotedFrom 12805376 provenance.