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- _4 value "Mice carrying the lymphoproliferation (lpr) mutation have defects in the Fas antigen gene (resulting in loss of Fas activity). The lpr mice develop lymphadenopathy and suffer from a systemic lupus erythematosus-like autoimmune disease, indicating an important role for Fas antigen in the negative selection of autoreactive T cells in the thymus." provenance.
- _4 wasQuotedFrom 1372394 provenance.