Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAZkGODnMcAqJuCuiSQIhE3M_pZR58vgwrQPWW17zFSMo#_7> ?p ?o ?g. }
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- _7 value "To study the involvement of PTB-mediated oligomerization in Dok function, we have generated Jurkat clones overexpressing Dok-1 or Dok-2 with a mutation that prevents oligomerization (in either the PTB domain or Tyr146 of Dok-1 and Tyr139 of Dok-2). These mutations abrogate CD2-induced phosphorylation and the ability of Dok-1 or Dok-2 to inhibit CD2-induced ERK1/2 and NFAT activation." provenance.
- _7 wasQuotedFrom 16177091 provenance.