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{ <http://www.tkuhn.ch/bel2nanopub/RA_6CJFzPa7nEqQ34PpqS5RxglqqIdnORcqdD5csRUhWw#_6> ?p ?o ?g. }
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To generate mice that express a constitutively active mutant of Hck (i.e., HckY499F), we used gene targeting in ES cells to introduce a tyrosine (Y499) to phenylalanine (F) substitution in exon 13 of the endogenous hck gene.
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_6
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