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- _5 value "Proteolysis of E-cadherin and the subsequent activation of ?-catenin are features of epithelial?mesenchymal transition, which occurs when cell adhesions are lost and the process of cell migration begins. Hence, the shedding of E-cadherin by ADAM10 modulates the subcellular localization of ?-catenin and downstream signalling to cyclin D1, enhancing cell proliferation42." provenance.
- _5 wasQuotedFrom 19005493 provenance.