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- _5 value "HGF induced tyrosine phosphorylation of c-Met at both the autophosphorylation site (pY1230/1234/12350) and the regulatory juxtamembrane c-Cbl binding site (pY1003). However, both of the tyrosine phospho-epitopes of c-Met were inhibited by pretreatment of SU11274 in a dose-dependent manner up to near basal level without affecting total steady-state c-Met protein level (Fig. 4C)." provenance.
- _5 wasQuotedFrom 16397249 provenance.