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- _4 value "Heeschen et al. (111) involved nAChR {alpha}7-dependent (nAChR = CHRNA7) signaling in angiogenesis, based on testing the effects of the nAChR {alpha}7-antagonist {alpha}-bungarotoxin in endothelial cells (lung endothelial cells). {alpha}7-Mediated endothelial cell angiogenic networking depended partly on vascular endothelial cell growth factor (VEGF) and was completely reliant on signaling by phosphoinositide 3-kinase (PI3K), ERK, and p38 mitogen-activated protein kinase (MAPK), finally resulting in NF-{kappa}B activation." provenance.
- _4 wasQuotedFrom 17615396 provenance.