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- _3 value "Although p53 promotes apoptosis in macrophages and endothelial cells, it protects vascular SMC from apoptosis [145], and the overall role of p53 was reported to be antiatherosclerotic in that p53 knockout mice demonstrated increased aortic plaque formation [145]. This is further demonstrated by the fact that the macrophagespecific loss of p53 induces larger aortic lesion size [146]." provenance.
- _3 wasQuotedFrom 18996472 provenance.