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- _4 value "Thimmulappa et al. (2006b) determined that CDDO-Im protects from deregulation of LPS-induced innate immune response in a Nrf2- dependent manner. Increased NADPH oxidase-dependent ROS generation and pro-inflammatory cytokine (TNF-? and IL-6), and chemokine (MIP2 and MCP-1) production were found in LPS-stimulated peritoneal neutrophils from Nrf2?/? mice relative to cells from Nrf2+/+ mice. " provenance.
- _4 wasQuotedFrom 19646463 provenance.