Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAbDcKlAWL0_712e9WdicOvrCtzWTfkPv2cuTOxNRmzVc#_6> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _6 value "Moreover, protein-DNA array studies identified two novel GSK-3-regulated transcription factors, early growth response 1 and Smad3/4, which were oppositely affected by GSK-3alpha or GSK-3beta silencing or inhibition Binding activity of EGR-1-responsive element with EGR-1 was down-regulated by transfection with siRNA for GSK-3{alpha} but up-regulated by siRNA for GSK-3beta compared with the non-targeting siRNA control. Luciferase reporter assays confirmed that the transcriptional activity of EGR-1 was decreased by GSK-3{alpha} siRNA and its dominant negative mutant but increased by GSK-3beta siRNA and its dominant negative mutants (Fig. 4A)." provenance.
- _6 wasQuotedFrom 16912034 provenance.